All secure transactions handled by CLIA ID NUMBER 99D0999287 LSPQ PERMIT 2120-1561 State of Florida Licence 800017961 State of Pennsylvania Licence Lab ID# 028731 Encryption Certificate Created by For any comment about this site:	Report from the Advisory Panel: National Forum on Hematopoietic Stem Cell Transplantation from Unrelated Donors. Ce rapport sera soumis en Février 2001 aux organismes gouvernementaux et nationaux suivants: Canadian Blood Services, Santé Canada, et le Canadian Blood and Marrow Transplant Group. Soiffer, R.J., Billet, A.L., Roy, D.C., Dalton, V., Tarbell, N.J., Sallan, S.E., Ritz, J.: Autologous Bone Marrow Transplantation for Acute Lymphoblastic Leukemia in Second or Subsequent Complete Remission: Ten Years Experience at Dana-Farber Cancer Institute. In: Dicke, K.A., Armitage, J.O., Dicke-Evinger, M.J. (eds): Autologous Bone Marrow Transplantation: Proc. of the 5 th International Symposium, 1991, 167-76, Omaha NE, 1990. Von Bueltzingsloewen, A., Gyger, M., Bélanger, R., Bonny, Y., Perreault, C., Boileau, J., Lavallée, R., Lacombe, M., Roy, G., Decary, F., Chabot, P., D'Angelo, G., Laplante, S., Filion, R. and Roy, D.C. Cost-Effec-tiveness of rh-GM-CSF in Autologous Bone Marrow Transplantation. In: Maroun, JA, Buskard, NA (eds): Colony-Stimulating Factors in Clinical Practice, London, Engl., Royal Society of Medicine Services, 1992, p. 31-38. Robertson, M.J., Roy, D.C., Stone, R.M., Ritz, J. Use of CD33 Monoclonal Antibodies in Bone Marrow Transplantation for Acute Myeloid Leukemia. In: Progress in Clinical and Biological Research; Advances in Bone Marrow Purging and Processing, Wiley Liss, 1994, p.47-63. Perreault, C., Roy, D.C. The Role of Minor Histocompatibility Antigens in Immunosurveillance and Transplantation. In: Rifle , G., Vuitton, D and Herve, P. (eds): Organ Transplantation and Tissue Grafting, John Libbey, 1994. Miron, P., Lachapelle, M.H., Roy, D.C.: Endometrial Immunology in Endometriosis; In: Proceedings of 5th World Congress on Endometriosis, Yokohama, Japon, 1996. Roy, D.C. Autologous Transplantation, In: Trudeau, M. (ed): Oncology Update: Advances in High-Dose Chemotherapy, The Medicine Group, 1998, p. 1-5. Beauger, N., Roy, D.C. Hematopoietic Progenitor-Cell Graft Processing and Treatment. In: Grossbard, M.L. (ed): Monoclonal Antibody-Based Therapy of Cancer, Marcel Dekker, Inc. 1998, p. 229-280. Roy, D.C., Beauger, N., Gyger, M. Bone Marrow Purging and Stem Cell Preparation. In: Matzku, S., Stahel, R.A. (eds): Antibodies in Diagnosis and Therapy: Technologies, Mechanisms and Clinical Data, Harwood Academic, 1999, p. 255-304. Perreault, C., Pion, S., Roy, D.C.: Mechanisms and Implications of Immunodominance. In: Roopenian, D.C., Simpson, E. (eds): Minor Histocompatibility Antigens: From the Laboratory to the Clinic, R.G. Landes, 1999, p. 71-78. Roy, D.C., Laporte, J., et Couture, J.: Corrélation entre les modifications de l'activité cérébrale et la chute de la CRF au cours de l'anesthésie au Thiopenthal. Rapport des travaux scientifiques, pro-gramme des stagiaires de la Faculté de Médecine, Presses de l'Université de Montréal 1978, 3:1-17. Roy, D.C., et Couture, J.: Etude de la capacité résiduelle fonctionnelle et de la mécanique respiratoire sous curarisation et après anesthésie. Rapport des travaux scientifiques, programme des stagiaires de la Faculté de Médecine, Presses de l'Université de Montréal 1979, 3:1-15. Roy, D.C., Havrankova, J., Belanger, R, Pomier, G., Tanguay, S., D'Amour, P., et Matte, R.: Localisation des insulinomes: utilité du dosage de l'insuline par cathétérisme transhépatique du réseau veineux pancréatique. Union méd. Can. 1985, 114:415-420. Roy, D.C., Felix, M., Cannady, W., Cannistra, S. and Ritz, J.: Comparative Activities of Rabbit Complements of Different Ages Using an In Vitro Marrow Purging Model. Leukemia Research 1990, 14:407-416. Roy, D.C., Tantravahi, R., Murray, C., Dear, K., Gorgone, B., Anderson, K.C., Freedman, A.S., Nadler, L.M. and Ritz, J.: Natural History of Mixed Chimerism Following Bone Marrow Transplantation with CD6 Depleted Allogeneic Marrow: A Stable Equilibrium. Blood 1990, 75:296-304. Perreault, C., Decary, F., Brochu, S., Gyger, M., Belanger, R and Roy, D.: Minor Histocompatibility Antigens. Blood 1990, 76:1269-1280. Roy, D.C., Griffin, J.D., Belvin, M., Blättler, W.A., Lambert, J.M. and Ritz, J.: Anti-MY9-Blocked-Ricin: An Immunotoxin for Selective Targeting of Acute Myeloid Leukemia Cells. Blood 1991, 77:2404-2412. Perreault, C., Belanger, R., Bonny, Y., Gyger, M. and Roy, D.C.: Critical Issues in Bone Marrow Transplantation Immunology. Bone Marrow Transplant. 1991, 7 Suppl.1:24-25. Gribben, J.G., Freedman, A.S., Neuberg, D., Roy, D.C., Blake, K.W., Woo, S.D., Grossbard, M.L., Coral, F., Freeman, G.J., Ritz, J. and Nadler, L.M.: Immunologic Purging of Polymerase Chain Reaction Detectable Lymphoma Cells Results in Increased Disease-Free Survival Following Autologous Bone Marrow Transplantation for B-Cell Non-Hodgkin's Lymphomas. N. Engl. J. Med. 1991, 325:1525-33. Gyger, M., D'Angelo, G., Bélanger, R., Forest, L., Lussier, P., Busque, L., Perreault, C., Boileau, J., Bonny, Y., Lavallée, R., Lacombe, M. and Roy, D.C.: Cytogenetic Characterization of Primary Refractory Anemia. Am. J. Hematol. 1992, 41:241-248. Brochu, S., Roy, D.C. and Perreault, C.: Tolerance to Host Minor Histocompatibility Antigens After Allogeneic Bone Marrow transplan-tation: Specific Donor-Host Unresponsiveness is Maintained by Peripheral Tolerizing Cells. J. Immunol. 1992, 149:3135-41. Von Bueltzingsloewen, A., Bélanger, R., Perreault, C., Bonny, Y., Roy, D.C., Lalonde, Y., Boileau, J., Kassis, J., Lavallée, R., Lacombe, M. and Gyger M.: Acute Graft-Versus-Host Disease Prophylaxis with Methotrexate and Cyclosporine Following Busulfan and Cyclophosphamide in Patients with Hematologic Malignancies. Blood 1993, 81:849-855. Soiffer, R.J., Roy, D.C., Anderson, K.C., Freedman, A.S., Gonin R., Murray, C., Rabinowe, S.N., Robertson, M.J., Spector, N., Unger, P.S., Blake, K., Mauch, P., Nadler L.M. and Ritz, J.: Monoclonal Antibody-Purged Autologous Bone Marrow Transplantation in Adults with Acute Lymphoblastic Leukemia in Second or Subsequent Remission. Bone Marrow Transplant. 1993, 12:243-251. Von Bueltzingsloewen, A., Bélanger, R., Perreault, C., Bonny, Y., Roy, D.C., Boileau, J., Kassis, J., Lavallée, R., Lacombe, M., Gyger, M.: Allogeneic Bone Marrow Transplantation Following Busulfan-Cyclophos-phamide With or Without Etoposide Conditioning Regimen for Patients With Acute Lymphoblastic Leukemia. Br. J. Haematol., 1993, 85: 706-713 Pichert, G., Alyea, E.P., Soiffer, R.J., Roy, D.C., Ritz, J.: Persistence of Myeloid Progenitor Cells Expressing bcr-abl mRNA After Allogeneic Bone Marrow Transplantation for Chronic Myelogenous Leukemia. Blood, 1994, 84: 2109-2114. Hétu, F., Coutlée, F., Roy, D.C.: A Non-Isotopic Nested Polymerase Chain Reaction Method to Quantitate Minimal Disease in Patients with Non-Hodgkin's Lymphoma. Mol. Cell. Probes, 1994, 8: 449-457. Roy, D.C., Bélanger, R., Gyger, Perreault, C., M., LeHouillier, C., Blättler, W., Lambert, J and Ritz, J.: Elimination of B-Lineage Leukemia and Lymphoma Cells from Bone Marrow Grafts Using Anti-B4-Blocked-Ricin Immunotoxin. J. Clin. Immunol., 1995, 15: 51-57. Pichert, G., Roy, D.C., Gonin, R., Alyea, E.P., Bélanger, R., Gyger, M., Perreault, C., Bonny, Y., Lerra, I., Murray, C., Soiffer, R.J., Ritz, J.: Distinct Patterns of Minimal Residual Disease Associated with Graft-Versus-Host Disease after Allogeneic Bone Marrow Transplantation for Chronic Myelogenous Leukemia. J. Clin. Oncol., 1995, 13: 1704-1713. Brochu, S., Baron, C., Hétu, F., Roy, D.C., Perreault, C.: Oligoclonal Expansion of Cytotoxic T Lymphocytes Directed Against a Restricted Number of Dominant Minor Histocompatibility Antigens in Hematopoietic Chimeras. J. Immunol., 1995, 155: 5104-5114. Lachapelle, M.H., Miron, P., Hemmings, R., Baron, C., Roy, D.C.: Flow-Cytometric Characterization of Hematopoietic cells in Non-Pregnant Human Endometrium. Am. J. Reprod. Immunol., 1996, 35: 5-13. Arbour, S., Toupin, S., Bélanger, R., Gyger, M., Hallé, J.P., Perreault, C. and Roy, D.C.: Phenotypic and Functional Characterization of Peripheral Blood and Bone Marrow Natural Killer Cells Prior to Autologous Transplantation. Bone Marrow Transplantation, 1996, 17: 315-322. Lachapelle, M.H., Hemmings, R., Roy, D.C., Falcone, T., Miron, P.: Flow-Cytometric Evaluation of Leukocyte Subpopulations in the Follicular Fluids of Infertile Patients. Fertil. Steril., 1996, 65: 1135-1140. Lachapelle, M.H., Miron, P., Hemmings, R., Roy, D.C.: Endometrial T, B and NK Cells in Patients with Recurrent Spontaneous Abortion: Altered Profile and Pregnancy Outcome. J. Immunol., 1996, 156; 4027-4034. Roy, D.C., Ouellet, S., LeHouillier, C., Lambert, J.M., Perreault, C.: Elimination of Neuroblastoma and Small Cell lung Cancer Cells With an Anti-NCAM Immunotoxin. J. Natl. Cancer Inst., 1996, 88: 1136-1145. Lapointe, C., Forest, L., Lussier, P., Busque, L., Lagacé, F., Perreault, C., Roy, D.C., Gyger, M.: Sequential Analysis of Early Hematopoietic Reconstitution Following Allogeneic Bone Marrow Transplantation with Fluorescence In Situ Hybridization (FISH). Bone Marrow Transplantation, 1996, 17: 1143-1148. Perreault, C., Jutras, J., Roy, D.C., Filep, J.G., Brochu, S.: Identification of an Immunodominant Mouse Minor Histocompatibility. J. Clin. Invest., 1996, 98: 622-628. Dulude, G., Brochu, S., Fontaine, P., Baron, C., Gyger, M., Roy, D.C., Perreault, C. Thymic and Extrathymic Differentiation/Expansion of T Lymphocytes Following Bone Marrow Transplantation in Irradiated Recipients. Exp. Hematol., 1997, 29: 992-1004. Goulet, A.C., Goldmacher, V.S., Lambert, J.M., Baron, C., Roy, D.C., Kouassi, E. Conjugation of Blocked Ricin to an Anti-CD19 Monoclonal Antibody Increases. Antibody Induced Cell Calcium Mobilization and CD19 Internalization. Blood, 1997, 90: 2364-2375. Léonard, B.M., Hétu, F., Busque, L., Gyger, M., Bélanger, R., Perreault, C., Roy, D.C.: Lymphoma Cell Burden in Progenitor Cell Grafts Measured by Competitive PCR: Less Than One Log Difference Between Bone Marrow and Peripheral Blood Sources. Blood, 1998, 91: 331-339. Gyger, M., Baron, C., Forest, L., Lussier, P., Lagacé, F., Bissonnette, I., Bélanger, R., Bonny, Y., Busque, L., Roy, D.C., Perreault, C.: Quantitative Assessment of Hematopoietic Chimerism after Allogeneic Bone Marrow Transplantation Has Predictive Value for the Occurence of Irreversible Graft Failure and Graft-Vs.-Host Disease. Exp. Hematol., 1998, 26: 426-434. Perreault, C., Roy, D.C., Fortin, C.: Immunodominant minor histocompatibility antigens: The major ones. Immunol. Today, 1998, 19: 69-74. Dulude, G., Roy, D.C., Perreault, C.: The Effect of Graft-versus-Host Disease on T Cell Production and Homeostasis. J. Exp. Med., 1999, 189: 1329-1341. Brochu, S., Rioux-Massé, B., Roy, J., Roy, D.C., Perreault, C. : Massive Activation-Induced Cell Death of Alloreactive T Cells With Apoptosis of Bystander Postthymic T Cells Prevents Immune Reconstitution in Mice With Graft-Versus-Host Disease. Blood 1999, 94 : 390-400. Song, W.J., Sullivan, M.G., Legare, R.D., Hutchings, S., Tan, X., Kufrin, D., Ratajczak, J., Resende, I.C., Haworth, C., Hock, R., Loh, M., Felix, C., Roy, D.C., Busque, L., Kurnit, D., Willman, C., Gewirtz, A.M., Speck, N.A., Bushweller, J.H., Li, F.P., Gardiner, K., Poncz, M., Maris, J.M., Gilliland, D.G. : Haploinsufficiency of CBFA2 Causes Familial Thrombocytopenia With Propensity to Develop Acute Myelogenous Leukaemia. Nature Genetics 1999, 23 : 166-175. Loyer, V., Fontaine, P., Pion, S., Hétu, F., Roy, D.C., Perreault, C.: The In Vivo Fate of Antigen-Presenting Cells Displaying Minor and/or MHC Differences is Regulated by CTLs Specific for Immunodominant Class I-Associated Epitopes. J. Immunol., 1999, 163 : 6462-6467. Guimond, M., Busque, L., Baron, C., Bonny, Y., Bélanger, R., Mattioli, J., Perreault, C., Roy, D.C.: Relapse After Bone Marrow Transplantation: Evidence for Distinct Immunologic Mechanisms Between Adult and Paediatric Populations. Br. J. Haematol., 2000, 109 : 130-137. Roy, D.C., Robertson, M.M., Lavoie, J., Bélanger, R., Gyger, M., Perreault, C., Soiffer, R.J., Ritz, J.: Anti-MY9-bR Purged Autologous Bone Marrow Transplantation for Patients with Acute Myeloid Leukemia. (en preparation) Mollica, L., Bélanger, R., Gyger, M., Busque, L., Kassis, J., Bonny, Y., Perreault, C., Roy, D.C.: Autologous Immunotoxin Purged Bone Marrow Transplantation for patients with Non-Hodgkin's Lymphoma. (en préparation) Guimond, M., Sidi Boumedine, R., Beauger, N., Balassy, A., Perreault, C., Roy, D.C. Defective Production of Dendritic Cells from Patients with Chronic Myeloid Leukemia. (en preparation). Beauger, N., Hétu, F., Roy, D.C.: Preferential Expansion of Normal Hematopoietic Progenitors over Chronic Myeloid Leukemia Precursors. (en préparation). ROY J, Snover D, Weisdorf S, Mulvahill A, Filipovich AH, Weisdorf DJ. Simultaneous upper and lower endoscopic biopsy in the diagnosis of intestinal graft-versus-host disease. Transplantation 51: 642-646, 1991. Weisdorf SA, ROY J, Snover D, Platt JL, Weisdorf DJ. Inflammatory cells in graft-versus-host disease of the rectum: immunopathologic analysis. Bone Marrow Transplantation 7: 297-301, 1991. ROY J, Vercellotti G, Fenderson M, Mulvahill A, Snover D, Weisdorf DJ. Isolated relapse of acute myelogenous leukemia presenting as a gastric ulcer. American Journal of Hematology 37: 270-273, 1991. ROY J, McGlave PB, Filipovich AH, Miller WJ, Blazar BR, Ramsay NKC, Kersey JH, Weisdorf DJ. Acute graft-versus-host disease following unrelated donor marrow transplantation: failure of conventional therapy. Bone Marrow Transplantation 10: 77-82, 1992. ROY J, Platt J, Weisdorf DJ. Immunopathology of upper gastrointestinal acute graft-versus-host disease: lymphoid cells and endothelial adhesion molecules. Transplantation 55: 572-578, 1993. ROY J, Blazar B, Ochs L, Weisdorf DJ. The tissue expression of cytokines in human acute cutaneous graft-versus-host disease. Transplantation 60: 343-348, 1995. ROY J. Bone marrow transplantation in the nineties : a review. Canadian Journal of Continuing Medical Education 7: 45-59, 1995. Cantin G, Delage R, ROY J, Marchand-Laroche D, Leblond PF. Granulocyte recovery after sequential transfusion of mobilized blood stem cell contentrates in syngeneic recipients. Bone Marrow Transplantation, 17: 347-350, 1996. Delage R, Demers C, Cantin G and ROY J. Treatment of essential thrombocythemia during pregnancy with interferon-(. Obstetrics and Gynecology, 87: 814-817, 1996. Ochs LA, Blazar BR, ROY J, Weisdorf DJ. Cytokine expression in human cutaneous chronic graft-versus-host disease. Bone Marrow Transplantation, 17: 1085-1092, 1996. ROY J, Delage R. To transfuse or not to transfuse: that is the question. Canadian Journal Diagnosis, 14: 101-115, 1997. Delage R, ROY J, Jacques L, Bernier V, Delage JM, Darveau A. Multiple bcl-2/Ig gene rearrangements in persistent polyclonal B cell lymphocytosis. British Journal of Haematology, 97: 589-595, 1997. ROY J, Delage R. La ponction-aspiration et la biopsie de moelle osseuse. Le Clinicien, 13: 149-160, 1998. ROY J, Demers C, Cantin G, Whittom R, Bernier V, Delage R. Large cell Lymphoma complicating persistent polyclonal B cell lymphocytosis. Leukemia, 12: 1026-1030, 1998. Delage R, ROY J, Jacques L and Darveau A. All patients with persistent polyclonal B cell lymphocytosis present bcl-2/Ig gene rearrangements. Leukemia and Lymphoma, 31:567-574,1998. LeBlanc R, ROY J, Demers C, Vu L, Cantin G. A prospective study of G-CSF effects on hemostasis in allogeneic blood stem cells donors. Bone Marrow transplantation, 23 : 991-996,1999. Brochu S, Rioux-Massé B, ROY J, Roy DC, Perrault C. Massive activation-induced cell death of alloreactive T cells with apoptosis of bystander postthymic T cells prevents immune re- constitution in mice with graft-versus-host disease. Blood, 94 : 390-400, 1999. G. Boivin, R. Bélanger, R. Delage, C. Béliveau, C.Demers, N. Goyette, and J.ROY. Quantitative analysis of cytomegalovirus (CMV) viremia using the pp65 antigenemia assay and the COBAS AMPLICOR CMV MONITOR PCR test after blood and marrow allogeneic transplantation. Journal of Clinical Microbiology, 38, 4356-4360, 2000. J. ROY, R. Delage, R. Bélanger, C. Béliveau, C. Demers, and G. Boivin. Short course of oral ganciclovir following intravenous ganciclovir for the treatment of positive cytomegalovirus antigenemia after allogeneic blood stem cells transplantation. Manuscript in preparation. R. LeBlanc, S. Montminy-Métivier, R. Bélanger, L. Busque, D. Fish, D-C. Roy, J. Kassis, J. Boileau, R. Lavallée, C. Perreault, D. Bélanger, F. Letendre, J. Hébert, G. Sauvageau and J. ROY. Allogeneic transplant for multiple myeloma: benefits of minimizing cumulative toxicity and maximizing graft-versus myeloma effect. Manuscript in preparation. Evidence that post-operative fibrinolytic shutdown is mediated by plasma factors which stimulate endothelial cell type I plasminogen activator inhibitor biosynthesis. Kassis J., Hirsh J, Podor TJ. Blood 80;7: 1758-1764, 1992. Acute graft-versus-host disease prophylaxis with methotrexate and cyclosporine following busulfan and cyclophosphamide in patients with hematological malignancies. von Buelzingsloewen A., Gyger M., Bélanger R., Perrault C., Bonny Y., Roy D.-C., Lalonde Y., Boileau J., Kassis J., Lavallée R., Lacombe M. Blood 81;3: 849-855, 1993. Allogeneic bone marrow transplantation following busulfan-cyclophosphamide with or without etoposide conditioning regimen for patients with acute lymphoblastic leukaemia. von Buelzingsloewen A., Bélanger R., Perrault C., Bonny Y., Roy D.-C., Boileau J., Kassis J., Lavallée R., Gyger M. British Journal of Haematology 85:706-713, 1993. Prevention of venous thromboembolism after knee arthroplasty - A Randomized, Double-Blind Trial Comparing Enoxaparin with Warfarin. Leclerc J.R., Geerts W.H., Desjardins L,, Laflamme G.H., L'Espérance B., Demers C., Kassis J., Cruickshank M., Withman L, Delorme F. Ann Intern Med. 1996; 124:619-626. A comparison of low-molecular-weight heparin administered primarily at home with unfractionated heparin administered in the hospital for proximal deep-vein thrombosis. Levine M., Gent M., Hirsh J., Leclerc J., Anderson D., Weitz J, Ginsberg J, Turpie A., Demers C., Kovacks M., Geerts W., Kassis J., Desjardins L., Cusson J., Cruickshank M., Powers P., Brien W., Haley S., Willan A. N Engl J Med 1996;334:661-681. Low molecular weight heparin is an effective and safe treatment for deep-vein thrombosis and pulmonary embolism. The COLUMBUS Investigators. New Engl J Med 1997; 337:657-662. The incidence of symptomatic venous thromboembolism during and after prophylaxis with enoxaparin: a multi-institutional cohort study in patients who underwent hip and knee arthroplasty. Leclerc J.R., Gent M., Hirsh J., Geerts W.H., Ginsberg J.S., for the Canadian Collaborative Group. Arch Int Med 1998 ; 158: 873-878. Familial antiphospholipid syndrome and HLA DR( Genes and coagulation profiles. Hudson N, Busque L, Rauch J, Kassis J. Fortin P. Arth and Rheum 1997 ; 40(10): 1907-1908. A comparison of three months of anticoagulation with extended anticoagulation for a first episode idiopathic venous thromboembolism. Kearon C, Gent M, Hirsh J, Weitz J, Kovacs MJ, Anderson DR, Turpie AG, Green D, Ginsberg JS, Wells P, MacKinnon B, Julian JA, Johnston M, Douketis J, Roberts R, van Nguyen P, Kassis J. Dolan S, Demers C, Desjardins L, Solymoss S, Trowbridge A. N Engl J Med 1999; 340: 901-907. A comparaison of Enoxaparin with placebo for the prevention of venous thromboembolism in acutely ill medical patients. Samara MM, Cohen AT, Darmon JY, Desjardins L, Eldor A, Janbon C, Leizopovicz A, Nguyen H, Olsson CG, Turpe AG, Weisslinger N, for the Prophylaxis in Medical Patients Group of Investigators (Kassis J.and others). N Engl J Med 1999; 341: 739-800. The safe use of epidural anesthesia after subcutaneaous injection of low-dose heparin in general abdominal surgery. Kassis J., Fugère F., Dubé S. Can J Surg 2000 ; 43 (4) : 289-294. Safety of withholding heparin in pregnant women with a history of venous throembolism. Brill-Edwards P, Ginsberg J, Gent M, Hirsh J, Burrows R, Kearon C, Geerts W, Kovacs M, Weitz J, Robinson S, Whittom R, Couture G for the Recurrence of Clot in This Pregnancy Study Group. N Engl J Med 2000 ; 343 : 1439-1444. Concomitance of IgG anticardiolipin antibodies and other immunologic and thrombophilic abnormalities increases the risk of thrombosis. Hudson M, Herr AL, Rauch J, Neville C, Seguin C, Kassis J. Busque L, Fortin PR. J Rheumatol ( in press). Hyperhomocysteinemia or acquired APC resistance combined to antiphospholipid antibodies is associated with increased risk for thrombosis. Kassis J. Neville C, Rauch J, Busque L, Lecompte M, Bigue C, Chang E, Fortin PR. (manuscript in preparartion) A synthetic pentasaccharide for the prevention of depp-vein thrombosis after total hip replacement. Turpie A.G.G., Gaullus A.S., Hoek J.A., For the Pentasaccharide Investigator. NEJM, 2001: 344; 619625 Disseminated intravascular coagulation. Kassis J. Union Médicale du Canada 1993; 122(2) : 91. La maladie thromboembolique à l'approche de l'an 2000. Kassis J. Le Clinicien 1997: 12(12) :89-93. Thrombocytopénie et thrombophlébite veineuse profonde. Guide thérapeutique en médecine interne. Montréal, Presse de l'Université de Montréal : 1997 245-8. Thrombocytopénie : portez une attention particulière à l'héparine. Kassis J. Le Clinicien 1998 : 13(8) : 123-129. Anesthésie loco-régionale : risques hémorragiques en présence de prophylaxie antithrombotique et bénéfices antithrombotiques. Guay J, Kassis J. Med Hyg 1999 ; 57 :144-147. Boileau J, Lavallée R, Lacombe M, Bonny Y, D'Angelo G. Anémie micro-angiopathique et grossesse gemellaire. Nouv. Rev. Fr. Hémato. 1971. D'Angelo G, Lacombe M, Lavallée R, Bonny Y, Boileau J. Fibrinogène Montréal. Vie Méd. Can. Français 2:1129-1135, 1973 Gyger M, Lamarche J, Boileau J, Lavallée R, Lacombe M, Bonny Y, D'Angelo G. Ressources de la biopsie médullaire. La Vie Médicale au Canada Français 2:1145-1151, 1973. Gyger M, Lamarche J, Boileau J, Lavallée R, Lacombe M, Bonny Y, D'Angelo G. Etude comparative de la moelle osseuse par biopsie et aspiration médullaire. Un Med Can 103:1433-1439, 1974 D'Angelo G, Lacombe M, Lemay J, Lavallée R, Bonny Y, Boileau J. Fibrinogen Montreal II. Thrombo Diath Haemorrh. 34:570, 1975. Perreault C, Lamarche J, Boileau J et coll. Myélofibrose et lésions de la microcirculation médullaire. Un Med Can 105:1650-1660, 1976. Gyger M, LeGresley L-P, Boulianne P, Lacombe M, Lavallée R, Bonny Y, Boileau J, D'Angelo G. Hétérogénéité clinique de la pneumopathie au Myleran: à propos de deux nouvelles observations et d'une revue de la littérature. Un Med Can 106:1522-1528, 1977. Lépine M, Boileau J, Lavallée R, Lacombe M, Bonny Y, Gyger M, D'Angelo G. Purpura cyclique par dysgénésie mégacaryocytaire. Un Med Can 107:1-3, 1978. Perreault C, Boileau J, Bonny Y, D'Angelo G, Gyger M, Lacombe M, Lavallée R. Transplantation de moelle osseuse. Traitement des aplasies médullaires. Un Med Can 110:264-268, 1981. Boileau J, Jiang Yi-Shou Zhang Jianian. Détection du "terminal déoxynucléotidyl transférase " (TdT) par immunofluorescence indirecte; outil diagnsotique essentiel dans les leucémies. Union Médicale du Canada, 111: 4, 1982. Gyger M, Perreault C, Boileau J, Aymard J-P, Bonny Y, Lacombe M, Lavallée R, D'Angelo G, Tawil E. Restoration of normal hematopoiesis by bone marrow ablation and allogeneic marrow transplantation in a case of Hodgkin's disease therapy-related preleukemia. Blood 61:1275-1277, 1983. Aymard J-P, Perreault C, Boileau J, Gyger M. Traitement de la leucémie myéloide chronique par greffe médullaire allogénique en phase chronique, à propos d'un cas. J Med Strasbourg 14:149-153, 1983. Perreault C, Boileau J, Bonny Y, Décary F, Demers J, Gyger M, Lapointe Y, Maheu M, Rybka W, Tawil E. Transplantation de moelle osseuse dans les aplasies médullaires. Un Med Can 112:426-428, 1983. Perreault C, Gyger M, Boileau J et al. Acute graft-versus-host disease in allogeneic bone marrow transplantation. Can Med Assoc J 129:969-974, 1983. Gyger M, Perreault C, Carnot J, Boileau J, Bonny Y. Treatment of therapy-induced preleukemic syndrome. Blut 48: 117-120, 1984. Gyger M, Forest L, Vuong T-E, Perreault C, Lavallée R, Lacombe M, Boileau J, D'Angelo G. Therapy-induced preleukaemia in patients treated for Hodgkin's lymphoma: clinical and therapeutic relevance of sequential chromosome banding studies. Br J Haematol 58:61-69, 1984. Perreault C, Cousineau S, D'Angelo G, Gyger M, Nepveu F, Boileau J, Bonny Y, Lacombe M, Lavallée R. Lymphoid interstitial pneumonia following allogeneic bone marrow transplantation: a possible manifestation of chronic graft-versus-host disease. Cancer 55: 1-9, 1985. Perreault C, Bonny Y, Gyger M, Bélanger R, Robitaille D, Boileau J, David Blanchard L, Charron M. Congenital T-cell deficiency with neutropenia and erythroblastopenia: correction following allogeneic bone marrow transplantation. Transplantation 39:321-323, 1985. Perreault C, Gyger M, Bonny Y, Bélanger R, Boileau J, Tawil E, David M, Lacombe M, Lavallée R, D'Angelo G, Cousineau S, Madore PR. Transplantation de moelle osseuse. Expérience du Centre Hospitalier Maisonneuve-Rosemont et mise à jour concernant les indications. Un. Méd. Can. 115:295-302, 1986. Gyger M, Perreault C, Bélanger R, Bonny Y, Tawil E, David M, Boileau J, Lacombe M, Lavallée R, D'Angelo G. Bone marrow tansplantation in chronic myelogenous leukemia: discriminating between good and standard risk patients in chronic phase. Int. J. Cell. Cloning 4:210-214, 1986. Gyger M, Perreault C, Bonny Y, Bélanger R, David M, Boileau J, Tawil E, Lavallée R, Lacombe M, D'Angelo G, Cousineau S. Leucémie aigue lymphoblastique et non lymphoblastique en première rémission complète: traitement de consolidatoin par chimio-radiothérapie intensive suivi de greffe médullaire allogénique HLA-A, B et Dr compatible. Un. Méd. Can. 115:699-702, 1986. Gyger M, Perreault C, Bélanger R, Bonny Y, David M, Boileau J, Lavallée R, Lacombe M, D'Angelo G, Tawil E. Transplantation médullaire allogénique et leucémie myéloide chronique en phase chronique et accélérée. Un. Méd. Can. 117:169-178, 1988. Perreault C, Boileau J, Gyger M, DeBellefeuille C, D'Angelo G, Bélanger R, Lacombe M, Lavallée R, Bonny Y, Paquin M, Brochu S. Chronic B-cell lymphocytosis. Eur J Haemat 42:361-367, 1989. Perreault C, Boileau J, Gyger M, DeBellefeuille C, D'Angelo G, Bélanger R, Lacombe M, Lavallée R, Bonny Y, Paquin M, Brochu S. Chronic B-cell lymphocytosis. Eur J Haemat 42:361-367, 1989. Gyger, M., D'Angelo, G., Bélanger, R., Forest, L., Lussier, P., Busque, L., Perreault, C., Boileau, J., Bonny, Y., Lavallée, R., Lacombe, M. and Roy, D.C.: Cytogenetic Characterization of Primary Refractory Anemia. Am. J. Hematol. 41:241-248, 1992. Von Bueltzingsloewen, A., Bélanger, R., Perreault, C., Bonny, Y., Roy, D.C., Lalonde, Y., Boileau, J., Kassis, J., Lavallée, R., Lacombe, M. and Gyger M.: Acute Graft-Versus-Host Disease Prophylaxis with Methotrexate and Cyclosporine Following Busulfan and Cyclophosphamide in Patients with Hematologic Malignancies. Blood 81:849-855, 1993. Von Bueltzingsloewen, A., Bélanger, R., Perreault, C., Bonny, Y., Roy, D.C., Boileau, J., Kassis, J., Lavallée, R., Lacombe, M., Gyger, M.: Allogeneic Bone Marrow Transplantation Following Busulfan-Cyclophos-phamide With or Without Etoposide Conditioning Regimen for Patients With Acute Lymphoblastic Leukemia. Br. J. Haematol., 85: 706-713, 1993. Von Bueltzingsloewen, A., Gyger, M., Bélanger, R., Bonny, Y., Perreault, C., Boileau, J., Lavallée, R., Lacombe, M., Roy, G., Décary, F., Chabot, P., D'Angelo, G., Laplante, S., Filion, R. and Roy, D.C. Cost-Effec-tiveness of rh-GM-CSF in Autologous Bone Marrow Transplantation. In: Maroun, JA, Buskard, NA (eds): Colony-Stimulating Factors in Clinical Practice, London, Engl., Royal Society of Medicine Services, 1992, p. 31-38. Tremblay R, Bonnardeaux A, Geadah D, Busque L, Lebrun M, Ouimet D, Lablanc M. Hyperhomocysteinemia in hemodyalisis patients: effects of 12-month supplementation with hydrosoluble vitamins. Kidney Int. 2000, 58:851-8. Guimond M, Busque L, Baron C, Bonny Y, Bélanger R, Mattioli J, Perreault C, Roy DC. Relapse after bone marrow transplantation: evidence for distinct immunological mechanisme between adault and paeditric populations. Br. J. Heamatology 2000, 109:130-7. SongWJ, Sullivan MG, Legare RD, Hutchings S, Tan X, Kufrin D Rataczac J, Resende JC, Haworth C, Hock R. Loh M, Felix C, Roy DC, Busque L, Kurnit D, Willman C, Gewirtz AM, Speck NA, Bushweller JH, LiFP, Gardiner K, Poncz M, Maris JM, Gilliland DG. Haploinsufficiency of CBFA2 causes familial thrombocyopenia with propensity to develop acute myelogenous leukemia. Nat. Genet 1999, 23:166-75 Desmarais D, Zhong Y, Chakraborty R, Perrault C, Busque L. Development of a highly polymorphic STR marker for forensic and parentage application at the human androgen receptor gene (HUMARA). J Forensic Sci, 1998, 43(5) : 1046-1049. Léonard BM, Hétu F, Busque L, Gyger M, Bélanger R, Perrault C, Roy DC. Lymphoma cell burden in progenitor cell grafts measured by competitive PCR : less than one log difference between bone marrow and peripheral blood sources. Blood, 1998, 91(1) : 331-339. Busque L, Gilliland DG. X-inactivation analysis in the 1990s : promise and potential problems. Leukemia, 1998, 12(2) : 128-135. Gyger M, Baron C, Forest L, Lussier P, Lagacé F, Bissonnette I, Bélanger R, Bonny Y, Busque L, Roy DC, Perreault C. Quantitative assessment of hematopoietic chimerism following allogeneic bone marrow transplantation has predictive value for occurence of irreversible graft versus host disease. J Exp Hem, 1998, 26(5) : 426-434. Hudson N, Busque L, Rauch J, Kassis J, Fortin PR, Familial antiphopholipid syndrome and HLA-DRB gene associations, Arthritis & Rheumatism, 1997, 40(10) :1907-1908. Busque L, Desmarais D, Provost S, Schumm JW, Zhong Y, Chakraborty R. Analysis of allele distribution for six short tandem repeat loci in the French Canadian population of Québec. J Forensic Sci 1997, 42(6) : 1147-1153. Lajeunesse R, Busque L, Ménard P, Brunette MG, Bonny Y. Demonstration of an osteoblast defect in two cases of human malignant osteopetrosi : is the osteoclast contributing to the differentiation of osteoblast? Journal of Clinical Investigation. 1996, 98 :1835-1842. Busque L, Gilliland DG. The PGK-PCR clonality assay (PPCA). Mol Biothecnol, 1996, 5 : 275-280. Lapointe C, Forest L, Lussier P, Busque L, Lagacé C, Perreault C, Roy DC and Gyger M. Sequential analysis of early hematopoietic reconstitution following allogeneic bone marrow transplantation with fluorescence in situ hybridization (FISH). Bone Marrow Transplantation, 1996, 17 : 1143-1148. Busque L, Mio R., Mattioli J, Brais E, Blais N, Maragh M, Gilliland DG. X-inactivation patterns in female: lyonization vary with age. Blood, 1996, vol. 88 : 59-65. Zhu J, Frosh PM, Busque L, Beggs AH., Dasher K, Gilliland DG, Black PMcl. Analysis of meningiomas by methylation-based and transcription-based clonality assay. Cancer Research 1995, 55 : 3865-3872. Leitenberg D, Eisen RN, Goldstein JN, Busque L, Rinder HM, Stys P, Katz ME, Gilliland DG, Smith BR. Natural killer cell lymphoproliferative disease associated with neuropathy. American Journal of Medicine, 1995, 99 : 99-101. Busque L, Gilliland G, Prchal JT, Sieff CA, Weinstein HJ, Sokol JM, Belichova M, Wayne AS, Zukerman KS, Sokol L, Castleberry R.P, Emanuel PD. Clonality in juvenile chronic myelegenous leukemia. Blood, 1995, 85 : 21-30. Busque L., and Gilliland D.G. Clonality analysis in disorders of myelopoiesis. Focus on growth factors. 1994, vol. 5, No.1. Busque L., and Gilliland D.G. The PGK-PCR based clonality assay (PPCA), in Adrian J, Hawood (ed) : Methods in molecular biology : Protocols for gene analysis, vol 31. Totowa NJ, Humana Press, 1994, 237-246. Willman C.H. Busque L., Griffith B., Favara B.E., McLain K.L., Duncan M.H. Gilliland D.G. Langerhans cell Histiocytosis (Histiocytose X): A clonal proliferative disease. New England Journal of Medicine, 1994, 331 : 154-160. Busque L., Zhu J., DeHart D., Griffith B., Willman C., Carrol R., Black P. M., and Gilliland D.G. An expression based clonality assay at the human androgen receptor locus (HUMARA) on chromosome X. Nucleic Acids Research, 1994, 22 : 697-698. Zhu J., Leon P.L., Beggs A.H., Busque L., Gilliland D.G., and Black P. Mcl., Human pituitary adenomas show no loss of heterozygosity at the retinoblastoma gene locus. The Journal of Clinical Endocrinology and Metabolism, 1994, 78 : 922-927. Busque L., Ilaria R., Tantravahi R., Weinstein H., and Gilliland D.G. Clonality analysis of childhood ALL in remission: no evidence for clonal hematopoiesis. Leukemia Research, 1994, 18 : 71-77. Busque L, Gilliland DG. Clonal evolution in acute Myeloid leukemia. Blood 1993,82 : 337-342. Gyger M, D'Angelo G, Bélanger R, Forest L, Lussier P, Busque L, Perreault C, Boileau J, Lavallée R, Lacombe M. Cytogenetic characterization of primary refractory anemia. Am J Hematol, 1992, 41 : 241-248. L'Abbé D, Tremblay L, Filion M, Busque L, Goldman M, Decarie F, Chartrand P. Alloimmunization to platelet HPA 1A (PLA1) is strongly associated with both HLA DRB3 0101 and HLA DQB 0201. Human Immunology, 1992, 34 : 106-114. Boileau J, Lavallée R, Lacombe M, Bonny Y, D'Angelo G. Anémie micro-angiopathique et grossesse gemellaire. Nouv. Rev. Fr. Hémato. 1971. D'Angelo G, Lacombe M, Lavallée R, Bonny Y, Boileau J. Fibrinogène Montréal. Vie Méd. Can. Français 2:1129-1135, 1973 Gyger M, Lamarche J, Boileau J, Lavallée R, Lacombe M, Bonny Y, D'Angelo G. Ressources de la biopsie médullaire. La Vie Médicale au Canada Français 2:1145-1151, 1973. Gyger M, Lamarche J, Boileau J, Lavallée R, Lacombe M, Bonny Y, D'Angelo G. Étude comparative de la moelle osseuse par biopsie et aspiration médullaire. Un Med Can 103:1433-1439, 1974 D'Angelo G, Lacombe M, Lemay J, Lavallée R, Bonny Y, Boileau J. Fibrinogen Montreal II. Thrombo Diath Haemorrh. 34:570, 1975. Perreault C, Lamarche J, Boileau J et coll. Myélofibrose et lésions de la microcirculation médullaire. Un Med Can 105:1650-1660, 1976. Gyger M, LeGresley L-P, Boulianne P, Lacombe M, Lavallée R, Bonny Y, Boileau J, D'Angelo G. Hétérogénéité clinique de la pneumopathie au Myleran: à propos de deux nouvelles observations et d'une revue de la littérature. Un Med Can 106:1522-1528, 1977. Lépine M, Boileau J, Lavallée R, Lacombe M, Bonny Y, Gyger M, D'Angelo G. Purpura cyclique par dysgénésie mégacaryocytaire. Un Med Can 107:1-3, 1978. Perreault C, Boileau J, Bonny Y, D'Angelo G, Gyger M, Lacombe M, Lavallée R. Transplantation de moelle osseuse. Traitement des aplasies médullaires. Un Med Can 110:264-268, 1981. Boileau J, Jiang Yi-Shou Zhang Jianian. Détection du "terminal déoxynucléotidyl transférase " (TdT) par immunofluorescence indirecte; outil diagnostique essentiel dans les leucémies. Union Médicale du Canada, 111: 4, 1982. Gyger M, Perreault C, Boileau J, Aymard J-P, Bonny Y, Lacombe M, Lavallée R, D'Angelo G, Tawil E. Restoration of normal hematopoiesis by bone marrow ablation and allogeneic marrow transplantation in a case of Hodgkin's disease therapy-related preleukemia. Blood 61:1275-1277, 1983. Aymard J-P, Perreault C, Boileau J, Gyger M. Traitement de la leucémie myéloïde chronique par greffe médullaire allogénique en phase chronique, à propos d'un cas. J Med Strasbourg 14:149-153, 1983. Perreault C, Boileau J, Bonny Y, Décary F, Demers J, Gyger M, Lapointe Y, Maheu M, Rybka W, Tawil E. Transplantation de moelle osseuse dans les aplasies médullaires. Un Med Can 112:426-428, 1983. Perreault C, Gyger M, Boileau J et al. Acute graft-versus-host disease in allogeneic bone marrow transplantation. Can Med Assoc J 129:969-974, 1983. Gyger M, Perreault C, Carnot J, Boileau J, Bonny Y. Treatment of therapy-induced preleukemic syndrome. Blut 48: 117-120, 1984. Gyger M, Forest L, Vuong T-E, Perreault C, Lavallée R, Lacombe M, Boileau J, D'Angelo G. Therapy-induced preleukaemia in patients treated for Hodgkin's lymphoma: clinical and therapeutic relevance of sequential chromosome banding studies. Br J Haematol 58:61-69, 1984. Perreault C, Cousineau S, D'Angelo G, Gyger M, Nepveu F, Boileau J, Bonny Y, Lacombe M, Lavallée R. Lymphoid interstitial pneumonia following allogeneic bone marrow transplantation: a possible manifestation of chronic graft-versus-host disease. Cancer 55: 1-9, 1985. Perreault C, Bonny Y, Gyger M, Bélanger R, Robitaille D, Boileau J, David Blanchard L, Charron M. Congenital T-cell deficiency with neutropenia and erythroblastopenia: correction following allogeneic bone marrow transplantation. Transplantation 39:321-323, 1985. Perreault C, Gyger M, Bonny Y, Bélanger R, Boileau J, Tawil E, David M, Lacombe M, Lavallée R, D'Angelo G, Cousineau S, Madore PR. Transplantation de moelle osseuse. Expérience du Centre Hospitalier Maisonneuve-Rosemont et mise à jour concernant les indications. Un. Méd. Can. 115:295-302, 1986. Gyger M, Perreault C, Bélanger R, Bonny Y, Tawil E, David M, Boileau J, Lacombe M, Lavallée R, D'Angelo G. Bone marrow tansplantation in chronic myelogenous leukemia: discriminating between good and standard risk patients in chronic phase. Int. J. Cell. Cloning 4:210-214, 1986. Gyger M, Perreault C, Bonny Y, Bélanger R, David M, Boileau J, Tawil E, Lavallée R, Lacombe M, D'Angelo G, Cousineau S. Leucémie aiguë lymphoblastique et non lymphoblastique en première rémission complète: traitement de consolidatoin par chimio-radiothérapie intensive suivi de greffe médullaire allogénique HLA-A, B et Dr compatible. Un. Méd. Can. 115:699-702, 1986. Gyger M, Perreault C, Bélanger R, Bonny Y, David M, Boileau J, Lavallée R, Lacombe M, D'Angelo G, Tawil E. Transplantation médullaire allogénique et leucémie myéloïde chronique en phase chronique et accélérée. Un. Méd. Can. 117:169-178, 1988. Perreault C, Boileau J, Gyger M, DeBellefeuille C, D'Angelo G, Bélanger R, Lacombe M, Lavallée R, Bonny Y, Paquin M, Brochu S. Chronic B-cell lymphocytosis. Eur J Haemat 42:361-367, 1989. Perreault C, Boileau J, Gyger M, DeBellefeuille C, D'Angelo G, Bélanger R, Lacombe M, Lavallée R, Bonny Y, Paquin M, Brochu S. Chronic B-cell lymphocytosis. Eur J Haemat 42:361-367, 1989. Gyger, M., D'Angelo, G., Bélanger, R., Forest, L., Lussier, P., Busque, L., Perreault, C., Boileau, J., Bonny, Y., Lavallée, R., Lacombe, M. and Roy, D.C.: Cytogenetic Characterization of Primary Refractory Anemia. Am. J. Hematol. 41:241-248, 1992. Von Bueltzingsloewen, A., Bélanger, R., Perreault, C., Bonny, Y., Roy, D.C., Lalonde, Y., Boileau, J., Kassis, J., Lavallée, R., Lacombe, M. and Gyger M.: Acute Graft-Versus-Host Disease Prophylaxis with Methotrexate and Cyclosporine Following Busulfan and Cyclophosphamide in Patients with Hematologic Malignancies. Blood 81:849-855, 1993. Von Bueltzingsloewen, A., Bélanger, R., Perreault, C., Bonny, Y., Roy, D.C., Boileau, J., Kassis, J., Lavallée, R., Lacombe, M., Gyger, M.: Allogeneic Bone Marrow Transplantation Following Busulfan-Cyclophos-phamide With or Without Etoposide Conditioning Regimen for Patients With Acute Lymphoblastic Leukemia. Br. J. Haematol., 85: 706-713, 1993. Von Bueltzingsloewen, A., Gyger, M., Bélanger, R., Bonny, Y., Perreault, C., Boileau, J., Lavallée, R., Lacombe, M., Roy, G., Décary, F., Chabot, P., D'Angelo, G., Laplante, S., Filion, R. and Roy, D.C. Cost-Effec-tiveness of rh-GM-CSF in Autologous Bone Marrow Transplantation. In: Maroun, JA, Buskard, NA (eds): Colony-Stimulating Factors in Clinical Practice, London, Engl., Royal Society of Medicine Services, 1992, p. 31-38. Bélanger R, Tutschka PJ, Beschorner WE, Santos GW. Acute graft-versus-host disease in recipients of syngeneic bone marrow. Exp Hematol 10:23-32, 1982. Tutschka PJ, Bélanger R, Hess AD, Beschorner WE, Santos GW. Suppressor cells in transplantation tolerance to self and non self. Transplant Proc 15:853-858, 1983. Gyger M, Perreault C, Bonny Y, Bélanger R. Chronic myeloid leukemia with an unusual simple variant translocation: t(22;22) (q13;q11). Acta Haemat 73:193-195, 1985 Perreault C, Pelletier M, Bélanger R, David M, Gyger M, Landry D, Montplaisir S. Persistence of host Langerhans cells following allogeneic bone marrow transplantation: possible relationship with acute graft-versus-host disease. Br J Haemat 60:253-260, 1985. Perreault C, Bonny Y, Gyger M, Bélanger R, Robitaille D, Boileau J, David M, Blanchard L, Charron M. Congenital T-cell deficiency with neutropenia and erythroblastopenia: correction following allogeneic bone marrow transplantation. Transplantation 39:321-323, 1985. Perreault C, Giasson OM, Gyger M, Bélanger R, David M, Bonny Y, Boileau J, Barcelo R. Study of serum immunoglobulin levels following allogeneic bone marrow transplantation. Blut 51:137-142, 1985. Roy DC, Havrankova J, Bélanger R, Pomier G, Tanguay S, D'Amour P, Matte R. : Localisation des insulinomes : utilité du dosage de l'insuline par cathétérisme transhépatique du réseau veineux pancréatique. Union méd. Can. 114:415-420, 1985. Perreault C, Gyger M, Bonny Y, Bélanger R, Boileau J, Tawil E, David M, Lacombe M, Lavallée R, D'Angelo G Cousineau S, Madore P-R. Transplantation de moelle osseuse. Expérience du centre hospitalier Maisonneuve-Rosemont et mise à jour concernant les indications. Un Med Can 115:295-302, 1986. Gyger M, Perreault C, Bélanger R, Bonny Y, Tawil E, David M, Boileau J, Lacombe M, Lavallée R, D'Angelo G. Bone marrow transplantation in chronic myelogenous leukemia: discriminating between good and standard risk patients in chronic phase. Int J Cell Cloning 4:210-214, 1986. Cousineau S, Bélanger R, Perreault C. Characterization of plasma cell populations at autopsy after human allogeneic bone marrow transplantation. Am J Pathol 124:74-81, 1986. Perreault C, Pelletier M, Bélanger R, Gyger M, David M, Bonny Y, D'Angelo G. The role of host bone marrow-derived cells in graft-versus-host disease. Int J Cell Cloning 4, suppl 1:189-190. 1986. Gyger M, Perreault C, Bonny Y, Bélanger R, David M, Boileau J, Tawil E, Lavallée R, Lacombe M, D'Angelo G, Cousineau S. Leucémie aigue lympho-blastique et non lymphoblastique en première rémission complète: traitement de consolidation par chimioradiothérapie intensive suivi de greffe médullaire allogénique HLA A, B et Dr compatible. Un Med Can 115:699-702, 1986. Bélanger R, Gyger M, Perreault C, Bonny Y, St-Louis J. Bone marrow trans-plantation for myelosysplastic syndromes. Br J Haematol 69:29-33, 1988. Gyger M, Perreault C, Bélanger R, Bonny Y, David M, Boileau J, Lavallée R, Lacombe M, D'Angelo G, Tawil E. Transplantation médullaire allogénique et leucémie myéloide chronique en phase chronique et accélérée. Un Med Can 117:169-178, 1988. Perreault C, Bélanger R, Gyger M, Allard A, Brochu S. The mechanism of graft-host-tolerance in murine radiation chimeras transplanted across minor histocompatibility barriers. Bone Marrow Transplant 4:83-87, 1989. Perreault C, Boileau J, Gyger M, De Bellefeuille C, D'Angelo G, Bélanger R, Lacombe M, Lavallée R, Bonny Y, Paquin M, Brochu S. Chronic B-cell lymphocytosis. Eur J Haemat 42:361-367, 1989. Gyger M, Perreault C, Bélanger R, Bonny Y, Forest L, Lussier P. Unsuspected Fanconi's anemia and bone marrow transplantation for acute myelomonocytic leukemia. N Engl J Med 321:120-121, 1989. Brochu S, Perreault C, Bélanger R. Evaluation of Fc-dependent monocyte-macrophage function in Bone Marrow Transplant reci-pients. Exp Hematol 17:948-951, 1989. Perreault C, Bélanger R, Gyger M, Brochu S. Réaction du greffon contre l'hôte et antigènes d'histocompatibilité mineurs. Médecine/Sciences 6:30-34, 1990. Perreault C, Allard A, Brochu S, Poupart C, Fontaine P, Bélanger R, Gyger M. Studies of immunologic tolerance to host minor histocompatibility antigens following allogeneic bone marrow transplantation in mice. Bone Marrow Transplant 6:127-135, 1990. Perreault C, Décary F, Brochu S, Gyger M, Bélanger R, Roy D-C. Minor histocompatibility antigens. Blood 76:1269-1280, 1990. Vézina D, Bélanger R, Bleau G. Micro-determination of selenium in protein fractions. Biol Trace Element Research 24:153-162, 1990. Perreault C, Bélanger R, Gyger M, Roy D-C. Critical issues in bone marrow trans-plantation immunology. Bone Marrow Transplant 7 supl 1:24-25, 1991. Gyger M, D'Angelo G, Bélanger R, Forest L, Lussier P, Busque L, Perreault C, Boileau J, Bonny Y, Lavallée R, Lacombe M, Roy D-C. Cytogenetic approach to the characterization of primary refractory anemia. Am J Hematol 41:241-248, 1992 von Bueltzingsloewen A, Gyger M, Bélanger R, Perreault C, Bonny Y, Roy DC, Lalonde Y, Boileau J, Kassis J, Lavallée R, Lacombe M. Acute graft-versus-host disease prophylaxis with methotrexate and cyclosporine following busulfan and cyclophosphamide in patients with hematological malignancies. Blood 81(3); 849-855, 1993. von Bueltzingsloewen A, Bélanger R, Perreault C, Bonny Y, Roy DC, Boileau J, Kassis J, Lavallée R, Gyger M. Allogeneic bone marrow transplantation following busulfan-cyclophosphamide with or without etoposide conditioning regimen for patients with acute lymphoblastic leukaemia. Br J Haematol 85: 706-713, 1993. Hébert MJ, Marion A, Boucher A, Dandavino R, Nolin L, Bélanger R, Madore F, Fish D. Mesangiolysis associated with bone marrow transplantation : new insights on possible etiogenic factors. Am J Kidney Dis Jun;23(6):882-3, 1994. Zizi L, Caron G, Bélanger R, Daigneault-Gélinas M. Comparaison de ltat en énergie et en protéines de patients ayant subi une transplantation médullaire allogénique versus autologue. Journal of the Canadian Dietetic Association, 55 (2), 1994. Brochu S, Baron C, Bélanger R, Perreault C. Graft-host tolerance in Bone Marrow Transplant chimeras. Absence of GVH is associated with unresponsiveness to minor histocompatibility antignes expressed on all organs. Blood 84; 3221-3228, 1994. Hébert MJ, Fish D, Madore F, Bélanger R, Nolin L, Dandavino R, Boucher A. Mesangyolysis associated with bone marrow transplantation. New insights on possible etrogenic factors. Am. J. Kidney Disease 23; 882-883, 1994 Jonea AR, Bélanger R, Blanchette VS, Card RT, Drouin J, Hume HA, Leclerc J, Meyer RM, Teitel JM. Development of High-Quality Royal College Written Examination : The Clinical Hematology Model. Annals RCPSC, 28(4), 1995. Roy DC, Perreault C, Bélanger R, Gyger M, Lehouillier C, Blattler WA, Lambert JM, Ritz H. Elimination of B-lineage leukemia and lymphoma cells from bone marrow graft using anti-B4-blocked-ricin immunotixin. J Clin Immunol. 15; 51057, 1995. Pichert G, Roy DC, Gonin R, Alyea EP, Bélanger R, Gyger M, Perreault C, Bonny Y, LERRA I, Murray C, Soiffer RH, Ritz J. Distinct patterns of minimal residual disease associated with graft-versus-host-disease after allogeneic bone marrow transplantation for chronic myelogenous leukemia. J. Clin. Oncol. 13; 1704-17173, 1995. Arbour S., Toupin S., Bélanger R., Gyger M., Hallé J.P., Perreault C. and Roy D.C.: Phenotypic and Functional Characterization of Peripheral Blood and Bone Marrow Natural Killer Cells Prior to Autologous Transplantation. Bone Marrow Transplantation1996, Mar;17(3):315-22. Léonard BM, Hétu F, Busque L, Gyger M, Bélanger R, Perreault C, Roy DC. : Lymphoma Cell Burden in Progenitor Cell Grafts Measured by competitive PCR : Less Than One Log Difference Between Bone and Peripheral Blood Sources. Blood ( sous presse). Gyger M, Baron C, Forest L, Lussier P, Lagacé F, Bissonnette I, Lapointe C, Bélanger R, Roy DC, Bonny Y, Busque L, Perreault C. : Quantitative Assessment of Hematopoietic Chimerism Following Allogeneic Bone Marrow Transplantation Has Predictive Value of the Occurrence of Irreversible Graft Failure and Graft Versus Host Disease. Exp. Hematol. (sous presse). Roy D.C., Robertson M.M., Bélanger R., Gyger M., Perreault C., Soiffer R.J., Ritz J.: Anti-MY9-bR Purged Autologous Bone Marrow Transplantation for Patients with Acute Myeloid Leukemia. (In preparation). Mollica L, Bélanger R, Gyger M, Busque L, Kassis J, Bonny Y, Perreault C, Roy DC. : Autologous Immunotoxin Purged Bone Marrow Transplantation for patients with Non-Hodgkin's Lymphome (en préparation). Bélanger R, Les anémies aplasiques et érythroblastopénie pure dans les anémies. îème édition, Les Presses de l'Université de Montréal, Masson 1994. Von Bueltzingsloewen A., Gyger M., Bélanger R., Bonny Y., Perreault C., Boileau J., Lavallée R., Lacombe M., Roy G, Décary F., CHABOT P., D'Angelo G., LAPLANTE S., FILION R. And Roy D.C. Cost-Effectiveness of rh-GM-CSF in Autologous Bone Marrow Transplantation. In: Maroun, JA, Buskard, NA (eds): Colony-Stimulating Factors in Clinical Practice, London, Engl., Royal Society of Medicine Services, 1992, p. 31-38. PERREAULT C, LAMARCHE J, BOILEAU J, LAVALLÉE R, LACOMBE M, BONNY Y, D'ANGELO MG. Myélofibrose et lésions de la microcirculation médullaire. Un Méd Can 105: 1650-1660, 1976. PERREAULT C. Les gènes de réponse immune. Rev Fr Transf Immuno-Hémat 21: 1131-1151, 1978. PERREAULT C, BOILEAU J, BONNY Y, D'ANGELO G, GYGER M, LACOMBE M, LAVALLEE R. Transplantation de moelle osseuse. Traitement des aplasies médullaires. Un Méd Can 110: 264-268, 1981. PERREAULT C. Le rôle du système HLA en transfusion et en transplantation médullaire. Un Méd Can 110: 318-324, 1981. PERREAULT C. Caractéristiques sérologiques des antigènes HLA-A, B et C. Can Med Assoc J 124: 690-697, 1981. GYGER M, PERREAULT C, FOREST L, D'ANGELO G. Leucémies aigues dimorphes et chromosome Philadelphie: expression phénotypique de l'atteinte d'une cellule souche lymphomyéloide. Un Méd Can 111: 429-437, 1982. GYGER M, PERREAULT C, BOILEAU J, AYMARD J-P, BONNY Y, LACOMBE M, LAVALLEE R, D'ANGELO G, TAWIL E. Restoration of normal hematopoiesis by bone marrow ablation and allogeneic marrow transplantation in a case of Hodgkin's disease therapy-related preleukemia.Blood 61: 1275-1277, 1983. RYBKA W, PERREAULT C, NOEL D. Le traitement de la leucémie aigue par transplantation médullaire: expérience québécoise. Un Méd Can 112: 444-447, 1983. AYMARD J-P, PERREAULT C, BOILEAU J, GYGER M. Traitement de la leucémie myéloide chronique par greffe médullaire allogénique en phase chronique, à propos d'un cas. J Méd Strasbourg 14: 149-153, 1983. PERREAULT C, BOILEAU J, BONNY Y, DECARY F, DEMERS J, GYGER M, LAPOINTE Y, MAHEU M, RYBKA W, TAWIL E. Transplantation de moelle osseuse dans les aplasies médullaires. Un Méd Can 112: 426-428, 1983. PERREAULT C, GYGER M, BOILEAU J et al. Acute graft-versus-host disease in allogeneic bone marrow transplantation. Can Med Assoc J 129: 969-974, 1983. GYGER M, PERREAULT C, CARNOT J, BOILEAU J, BONNY Y. Treatment of therapy-induced preleukemic syndrome. Blut 48: 117-120, 1984. PERREAULT C, PELLETIER M, LANDRY D, GYGER M. Study of Langerhans cells after allogeneic bone marrow transplantation. Blood 63: 807-811, 1984. GYGER M, FOREST L, VUONG T-E, PERREAULT C, LAVALLEE R, LACOMBE M, BOILEAU J, D'ANGELO G. Therapy-induced preleukaemia in patients treated for Hodgkin's lymphoma: clinical and therapeutic relevance of sequential chromosome banding studies. Br J Haematol 58: 61-69, 1984. PELLETIER M, PERREAULT C, LANDRY D, DAVID M, MONTPLAISIR S. Ontogeny of human epidermal Langerhans cells. Transplantation 38: 544-546, 1984. PERREAULT C, COUSINEAU S, D'ANGELO G, GYGER M, NEPVEU F, BOILEAU J, BONNY Y, LACOMBE M, LAVALLEE R. Lymphoid interstitial pneumonia following allogeneic bone marrow transplantation: a possible manifestation of chronic graft-versus-host disease. Cancer 55: 1-9, 1985. PERREAULT C, BONNY Y, GYGER M, BÉLANGER R, ROBITAILLE D, BOILEAU J, DAVID M, BLANCHARD L, CHARRON M. Congenital T-cell deficiency with neutropenia and erythroblastopenia: correction following allogeneic bone marrow transplantation. Transplantation 39: 321-323, 1985. PERREAULT C, PELLETIER M, BÉLANGER R, DAVID M, GYGER M, LANDRY D, MONTPLAISIR S. Persistence of host Langerhans cells following allogeneic bone marrow transplantation: possible relationship with graft-versus-host disease Br J Haematol 60: 253-260, 1985. PERREAULT C, GIASSON M, GYGER M, BÉLANGER R, DAVID M, BONNY Y, BOILEAU J, BARCELO R. Study of serum immunoglobulin levels following allogeneic bone marrow transplantation. Blut 51: 137-142, 1985. GYGER M, LAVERDIERE M, GAGNON A, PERREAULT C, COUSINEAU S, FOREST L. 14q+ abnormality with probable t(8;14)(q24;q32) in a young haitian immigrant with acquired immunodeficiency syndrome and concomitant Burkitt's like lymphoma. Cancer Genet Cytogen 17: 283-288, 1985. GYGER M, PERREAULT C, BÉLANGER R, BONNY Y. Chronic myeloid leukemia with an unusual simple variant translocation: t(22;22) (q13;q11). Acta Haematologica 73: 193-195, 1985. GYGER M, PERREAULT C, PICHETTE R, FOREST L, LUSSIER P. Interstitial deletion of the long arm of chromosome 5 (5q-) in leukemia and other hematological disorders: clinical and biological relevance of variable breakpoint patterns. Leukemia Research 10: 9-15, 1986. PERREAULT C, GYGER M, BONNY Y, BÉLANGER R, BOILEAU J, TAWIL E, DAVID M, LACOMBE M, LAVALLEE R, D'ANGELO G, COUSINEAU S, MADORE P-R. Transplantation de moelle osseuse. Expérience du centre hospitalier Maisonneuve-Rosemont et mise à jour concernant les indications. Un Méd Can 115: 295-302, 1986. COUSINEAU S, BÉLANGER R, PERREAULT C. Characterization of plasma cell populations at autopsy after human allogeneic bone marrow transplantation. Am J Pathol 124: 74-81, 1986. PELLETIER M, TAUTU C, LANDRY D, MONTPLAISIR S, CHARTRAND C, PERREAULT C. Characterization of human thymic dendritic cells in culture. Immunology 58: 263-270, 1986. GYGER M, PERREAULT C, BÉLANGER R, BONNY Y, TAWIL E, DAVID M, BOILEAU J, LACOMBE M, LAVALLEE R, D'ANGELO G. Bone marrow transplantation in chronic myelogenous leukemia: discriminating between good and standard risk patients in chronic phase. Int J Cell Cloning 4: 210-214, 1986. PERREAULT C, PELLETIER M, BÉLANGER R, GYGER M, DAVID M, BONNY Y, D'ANGELO G. The role of host bone marrow-derived cells in graft-versus-host disease. Int J Cell Cloning 4, suppl 1, 189-190, 1986. GYGER M, PERREAULT C, FOREST L, LUSSIER P, PICHETTE R. La délétion des bras longs du chromosome 5 en hématologie: intérêt clinique et biologique. Un Méd Can 115: 319-322, 1986. GYGER M, PERREAULT C, BONNY Y, BÉLANGER R, DAVID M, BOILEAU J, TAWIL E, LAVALLEE R, LACOMBE M, D'ANGELO G, COUSINEAU S. Leucémie aigue lymphoblastique et nonlymphoblastique en première rémission complète: traitement de consolidation par chimioradiothérapie intensive suivi de greffe médullaire allogénique HLA A, B et Dr compatible. Un Méd Can 115: 699-702, 1986. BARTHELEMY H, PELLETIER M, LANDRY D, PERREAULT C, TAUTU C, MONT-PLAISIR S. Demonstration of OKT6 antigen on human thymic dendritic cells in culture. Lab Invest 55: 540-545, 1987. BÉLANGER R, GYGER M, PERREAULT C, BONNY Y, ST-LOUIS J. Bone marrow transplantation for myelodysplastic syndromes. Br J Haematol 69: 29-33, 1988. GYGER M, PERREAULT C, BÉLANGER R, BONNY Y, DAVID M, BOILEAU J, LAVALLEE R, LACOMBE M, D'ANGELO G, TAWIL E. Transplantation médullaire allogénique et leucémie myéloide chronique en phase chronique et accélérée. Un Méd Can 117: 169-178, 1988. PERREAULT C, BÉLANGER R, GYGER M, ALLARD A, BROCHU S. The mechanism of graft-host-tolerance in murine radiation chimeras transplanted across minor histocompatibility barriers. Bone Marrow Transplant 4: 83-87, 1989. PERREAULT C, BOILEAU J, GYGER M, DeBELLEFEUILLE C, D'ANGELO G, BÉLANGER R, LACOMBE M, LAVALLEE R, BONNY Y, PAQUIN M, BROCHU S. Chronic B-cell lymphocytosis. Eur J Haemat 42: 361-367, 1989. BROCHU S, PERREAULT C, BÉLANGER R. Evaluation of Fc-dependent monocyte-macrophage function in bone marrow transplant recipients. Exp Hematol 17: 948-951, 1989. PERREAULT C, BÉLANGER R, GYGER M, BROCHU S. Réaction du greffon contre l'hôte et antigènes d'histocompatibilité mineurs. Médecine/Sciences 6: 30-34, 1990. FONTAINE P, PERREAULT C. Diagnosis of graft-versus-host disease in mice transplanted across minor histocompatibility barriers. Transplantation 49: 1177-1179, 1990. PERREAULT C, ALLARD A, BROCHU S, POUPART C, FONTAINE P, BÉLANGER R, GYGER M. Studies of immunologic tolerance to host minor histocompatibility antigens following allogeneic bone marrow transplantation in mice. Bone Marrow Transplant 6: 127-135, 1990. PERREAULT C, DECARY F, BROCHU S, GYGER M, BÉLANGER R, ROY D-C. Minor histocompatibility antigens. Blood 76: 1269-1280, 1990. PERREAULT C, BÉLANGER R, GYGER M, ROY D-C. Critical issues in bone marrow transplantation immunology. Bone Marrow Transplant 7 suppl 1:24-25, 1991. PERREAULT C. Utilisation du système HLA et des antigènes érythrocytaires dans les études de filiation. Congrès annuel du Barreau du Québec (1991), Service de la formation permanente du Barreau du Québec, Montréal, 1991, p. 383-388. FONTAINE P, LANGLAIS J, PERREAULT C. Evaluation of in vitro cytotoxic T lymphocyte assays as a predictive test for the occurrence of graft-versus-host disease. Immunogenetics 34: 222-226, 1991. GYGER M, D'ANGELO G, BÉLANGER R, FOREST L, LUSSIER P, BUSQUE L, PERREAULT C, BOILEAU J, BONNY Y, LAVALLEE R, LACOMBE M, ROY DC. Cytogenetic approach to the characterization of primary refractory anemia. Am J Hemat 41: 241-248, 1992. BROCHU S, ROY D-C, PERREAULT C. Tolerance to host minor histocompatibility antigens following allogeneic bone marrow transplantation. Specific donor-host unresponsiveness is maintained by peripheral tolerizing cells. J Immunol 149: 3135-3141, 1992. VON BUELTZINGSLOEWEN A, BÉLANGER R, PERREAULT C, BONNY Y, ROY D-C, LALONDE Y, BOILEAU J, KASSIS J, LAVALLEE R, LACOMBE M, GYGER M. Acute GVHD prophylaxis with methotrexate and cyclosporine in patients with hematological malignancies treated with busulfan and cyclophosphamide. Blood 81: 849-855, 1993. VON BUELTZINGSLOEWEN A, BÉLANGER R, PERREAULT C, BONNY Y, ROY DC, BOILEAU J, KASSIS J, LACOMBE M, GYGER M. Allogeneic bone marrow transplantation following busulfan-cyclophosphamide ± etoposide conditioning regimen for patients with acute lymphoblastic leukaemia. Br J Haematol 85: 706-713, 1993. BROCHU S, PERREAULT C. Functional evaluation of mouse bone marrow T lymphocytes. Transplantation 56: 1263-1265, 1993. PERREAULT C, BROCHU S, FONTAINE P, TREMBLAY N, PION S. The role of MHC-associated self peptides in transplantation and immunosurveillance. Clin Immunol Immunopathol 71: 130-135, 1994. TREMBLAY N, FONTAINE P, PERREAULT C. T lymphocyte responses to multiple minor histocompatibility antigens generate both self-MHC restricted and cross-reactive CTL. Transplantation 58: 59-67, 1994. PERREAULT C. Rôle des systèmes mineurs d'histocompatibilité dans l'immunosurveillance T-dépendante et en transplantation, in Transplantation d'organes et greffe de tissus, Hervé P, Rifle G, Vuitton D, Dureau G, Bechtel P, Justrabo E, Editions INSERM, Paris, 1994, p.139-147. BROCHU S, BARON C, BÉLANGER R, PERREAULT C. Graft-host tolerance in bone marrow transplant chimeras. Absence of GVH is associated with unresponsiveness to minor histocompatibility antigens expressed on all organs. Blood 84:3221-3228, 1994. PION S, FONTAINE P, BARON C, GYGER M, PERREAULT C. Immunodominant minor histocompatibility antigens expressed by mouse leukemic cells can serve as effective targets for T cell immunotherapy. J Clin Invest 95: 1561-1568, 1995. ROY DC, PERREAULT C, BÉLANGER R, GYGER M, LEHOUILLIER C, BLATTLER WA, LAMBERT JM, RITZ J. Elimination of B-lineage leukemia and lymphoma cells from bone marrow grafts using anti-B4-blocked-ricin immunotoxin. J Clin Immunol 15: 51-57, 1995. PICHERT G, ROY DC, GONIN R, ALYEA EP, BÉLANGER R, GYGER M, PERREAULT C, BONNY Y, LERRA I, MURRAY C, SOIFFER RJ, RITZ J. Distinct patterns of minimal residual disease associated with graft-versus-host disease after allogeneic bone marrow transplantation for chronic myelogenous leukemia. J Clin Oncol 13: 1704-1713, 1995. BROCHU S, BARON C, HETU F, ROY DC, PERREAULT C. Oligoclonal expansion of cytotoxic T lymphocytes directed against a restricted number of dominant minor histocompatibiltiy antigens in hematopoietic chimeras. J Immunol 155: 5104-5114, 1995. PERREAULT C. The role of minor histocompatibility antigens in T-cell immunosurveillance and transplantation, in Organ Transplantation and Tissue Grafting. Hervé P, Rifle G, Vuitton D, Dureau G, Bechtel P, Justrabo E. John Libbey and Co. Ltd., London, 1995, p119-125. ARBOUR S, TOUPIN S, BÉLANGER R, GYGER M, HALLE JP, PERREAULT C, ROY DC. Phenotypic and functional characterization of peripheral blood and bone marrow natural killer cells prior to an autologous transplantation. Bone Marrow Transplant 17: 315-322, 1996 LAPOINTE C, FOREST L, LUSSIER P, BUSQUE L, LAGACE F, PERREAULT C, ROY DC, GYGER M. Sequential analysis of early hematopoietic reconstitution following allogeneic bone marrow transplantation with fluorescence in situ hybridization (FISH). Bone Marrow Transplant 17: 1143-1148, 1996. MORSE MC, BLEAU G, DABHI VM, HETU F, DROBETSKY EA, FISCHER LINDAHL K, PERREAULT C. The COI mitochondrial gene encodes a minor histocompatibility antigen presented by H2-M3. J Immunol 156: 3301-3307, 1996. FILEP JG, BARON C, LACHANCE S, PERREAULT C, CHAN JSD. Involvement of nitric oxide in target cell lysis and DNA fragmentation induced by murine natural killer cells. Blood 87: 5136-5143, 1996. PERREAULT C, JUTRAS J, ROY DC, FILEP JG, BROCHU S. Identification of an immunodominant mouse minor histocompatibility antigen (MiHA): T cell response to a single dominant MiHA causes graft-versus-host disease. J Clin Invest 98: 622-628, 1996. (This paper was highlighted as "of outstanding interest" in Curr. Opin. Immunol. 9: 655-661, 1997) ROY DC, OUELLET S, LEHOUILLIER C, ARINIELLO PD, PERREAULT C, LAMBERT JM. Elimination of neuroblastoma and small-cell lung cancer cells with an anti-neural cell adhesion molecule immunotoxin. J Natl Cancer Inst 88: 1136-1145, 1996. PION S, FONTAINE P, DESAULNIERS M, JUTRAS J, FILEP JG, PERREAULT C. On the mechanisms of immunodominance in cytotoxic T lymphocyte responses to minor histocompatibility antigens. Eur J Immunol 27: 421-430, 1997 (This paper was highlighted as "of special interest" in Curr. Opin. Immunol. 9: 655-661, 1997). DULUDE G, BROCHU S, FONTAINE P, BARON C, GYGER M, ROY DC, PERREAULT C. Thymic and extrathymic differentiation/expansion of T lymphocytes following bone marrow transplantation in irradiated recipients. Exp Hematol 25: 992-1004, 1997. LÉONARD B, HÉTU F, BUSQUE L, GYGER M, BÉLANGER R, PERREAULT C, ROY DC. Lymphoma cell burden in progenitor cell grafts measured by competitive PCR: less than one log difference between bone marrow and peripheral blood sources. Blood 91: 331-339, 1998. PERREAULT C, ROY DC, FORTIN C. Immunodominant minor histocompatibility antigens: the major ones. Immunol. Today 19: 69-74, 1998. GYGER M, BARON C, FOREST L, LUSSIER P, LAGACE F, BISSONNETTE I, BÉLANGER R, BONNY, BUSQUE L, ROY DC, PERREAULT C. Quantitative assessment of hematopoietic chimerism following allogeneic bone marrow transplantation has predictive value for the occurrence of irreversible graft failure and graft versus host disease. Exp Hematol 26: 426-434, 1998. DESMARAIS D, ZHONG Y, CHAKRABORTY R, PERREAULT C, BUSQUE L. Development of a highly polymorphic STR marker for identity testing purposes at the human androgen receptor gene (HUMARA). J. Forensic Sci 43: 1046-1049, 1998. PION S, CHRISTIANSON GJ, FONTAINE P, ROOPENIAN DC, PERREAULT C. Shaping the repertoire of cytotoxic T lymphocyte (CTL) responses. The molecular bases of the immunodominance effect whereby CTLs specific for immunodominant antigens prevent recognition of nondominant antigens. Blood 93: 952-962, 1999. EDEN PA, CHRISTIANSON GJ, FONTAINE P, WETTSTEIN PJ, PERREAULT C, ROOPENIAN DC. Biochemical and immunogenetic analysis of an immunodominant peptide (B6dom1) encoded by the classical H7 minor histocompatibility locus. J Immunol 162: 4502-4510, 1999. DULUDE G, ROY DC, PERREAULT C. The effect of graft-versus-host disease on T cell production and homeostasis. J Exp Med 189: 1329-1341, 1999. MOREAU R, FRANK PG, PERREAULT C, MARCEL YL, MANJUNATH P. Seminal plasma choline phospholipid-binding proteins stimulate cellular cholesterol and phospholipid efflux. Biochim Biophys Acta 1438: 38-46, 1999. BROCHU S, RIOUX-MASSÉ B, ROY J, ROY DC, PERREAULT C. Massive activation-induced cell death of alloreactive T cells with apoptosis of bystander post-thymic T cells prevents immune reconstitution in mice with graft-versus-host disease. Blood 94: 390-400, 1999. LOYER V, FONTAINE P, PION S, HÉTU F, ROY DC, PERREAULT C. The in vivo fate of APCs displaying minor H antigen and/or MHC differences is regulated by CTLs specific for immunodominant class I-associated epitopes. J Immunol 163: 6462-6467, 1999. PERREAULT C, PION S, ROY DC. Mechanisms and implications of immunodominance, in Roopenian D, Simpson E (eds): Minor Histocompatibility Antigens: From the Laboratory to the Clinic, Landes Bioscience, Georgetown, chapter 7: 71-78, 2000. BOILEAU C, HOUDE M, DULUDE G, CLEGG CH, PERREAULT C. Regulation of extrathymic T cell development and turnover by Oncostatin M. J Immunol 164: 5713-5720, 2000. GYGER M, STUART RK, PERREAULT C. Immunobiology of allogeneic peripheral blood mononuclear cells mobilized with granulocyte colony-stimulating factor. Bone Marrow Transplant 26: 1-16, 2000. GUIMOND M, BUSQUE L, BARON C, BONNY Y, BÉLANGER R, MATTIOLI J, PERREAULT C, ROY DC. Relapse after bone marrow transplantation: Evidence for distinct immunologic mechanisms between adult and paediatric populations. Br J Haematol 109: 130-137, 2000. FONTAINE P, KNAFO L, BARON C, ROY-PROULX G, ROY DC, PERREAULT C. Adoptive transfer of T lymphocytes targeted to a single immunodominant minor histocompatibility antigen eradicates leukemia cells without causing graft-versus-host disease. Nature Medicine 7: 789-794, 2001. ROY-PROULX G, MEUNIER MC, LANTEIGNE AM, BROCHU S, PERREAULT C. Immunodomination results from functional differences between competing CTLs, Eur J Immuno 31: 2284-2292, 2001. Analysis of Allele Distribution for Six Short Tandem Repeat Loci in the French Canadian Population of Québec
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